Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50257608
Substrate
n/a
Meas. Tech.
ChEMBL_1689971 (CHEMBL4040541)
IC50
16±n/a nM
Citation
 Shi, Y; Duan, YH; Ji, YY; Wang, ZL; Wu, YR; Gunosewoyo, H; Xie, XY; Chen, JZ; Yang, F; Li, J; Tang, J; Xie, X; Yu, LF Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis. J Med Chem 60:7067-7083 (2017) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50257608
Synonyms:
CHEMBL4086928
Type:
Small organic molecule
Emp. Form.:
C26H35N3O3
Mol. Mass.:
437.5744
SMILES:
COc1cccc2c(cn(CCN3CCOCC3)c12)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:26:23.24.29:30,THB:25:24:30:31.26.27,27:26:23:29.28.30,27:28:23:31.25.26|
Structure:
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