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TargetAngiotensin II AT1B
LigandBDBM50010146
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36481
IC50 200±n/a nM
Citation Bühlmayer, PCriscione, LFuhrer, WFuret, Pde Gasparo, MStutz, SWhitebread, S Nonpeptidic angiotensin II antagonists: synthesis and in vitro activity of a series of novel naphthalene and tetrahydronaphthalene derivatives. J Med Chem34:3105-14 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II AT1B
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:AT1B | AT3 | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | Type-1B angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40929.44
Organism:RAT
Description:Angiotensin II AT1B 0 RAT::P29089
Residue:359
Sequence:
MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50010146
NameBDBM50010146
Synonyms:CHEMBL322683 | {2-Butyl-5-chloro-1-[6-(1H-tetrazol-5-yl)-naphthalen-2-ylmethyl]-1H-imidazol-4-yl}-methanol
TypeSmall organic molecule
Emp. Form.C20H21ClN6O
Mol. Mass.396.873
SMILESCCCCc1nc(CO)c(Cl)n1Cc1ccc2cc(ccc2c1)-c1nnn[nH]1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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