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Target
D(2) dopamine receptor
Ligand
BDBM50010616
Substrate
n/a
Meas. Tech.
ChEBML_61576
IC50
75±n/a nM
Citation
 Liljefors, T; Bøgesø, KP; Hyttel, J; Wikström, H; Svensson, K; Carlsson, A Pre- and postsynaptic dopaminergic activities of indolizidine and quinolizidine derivatives of 3-(3-hydroxyphenyl)-N-(n-propyl)piperidine (3-PPP). Further developments of a dopamine receptor model. J Med Chem 33:1015-22 (1990) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50010616
Synonyms:
(+)-3-(Octahydro-indolizin-8-yl)-phenol | (-)-3-(Octahydro-indolizin-8-yl)-phenol | 3-(Octahydro-indolizin-8-yl)-phenol | CHEMBL268240 | isomer-13-(Octahydro-indolizin-8-yl)-phenol | isomer-23-(Octahydro-indolizin-8-yl)-phenol
Type:
Small organic molecule
Emp. Form.:
C14H19NO
Mol. Mass.:
217.3068
SMILES:
Oc1cccc(c1)C1CCCN2CCCC12
Structure:
Search PDB for entries with ligand similarity: