Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50005400
Substrate
n/a
Meas. Tech.
ChEMBL_29295 (CHEMBL640356)
Ki
78±n/a nM
Citation
 Shimada, J; Suzuki, F; Nonaka, H; Karasawa, A; Mizumoto, H; Ohno, T; Kubo, K; Ishii, A 8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities. J Med Chem 34:466-9 (1991) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
GUINEA PIG
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50005400
Synonyms:
1,3-Dipropyl-8-(1-propyl-butyl)-3,7-dihydro-purine-2,6-dione | CHEMBL356458
Type:
Small organic molecule
Emp. Form.:
C18H30N4O2
Mol. Mass.:
334.4564
SMILES:
CCCC(CCC)c1nc2n(CCC)c(=O)n(CCC)c(=O)c2[nH]1
Structure:
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