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TargetC5a anaphylatoxin chemotactic receptor (C5aR)
LigandBDBM50012290
Substrate/Competitorn/a
Meas. Tech.ChEMBL_41599
Ki 150000±n/a nM
Citation Kawai, MQuincy, DALane, BMollison, KWLuly, JRCarter, GW Identification and synthesis of a receptor binding site of human anaphylatoxin C5a. J Med Chem34:2068-71 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C5a anaphylatoxin chemotactic receptor (C5aR)
Name:C5a anaphylatoxin chemotactic receptor
Synonyms:C5a anaphylatoxin chemotactic receptor | C5a-R | C5aR | CD_antigen=CD88
Type:Enzyme
Mol. Mass.:39347.68
Organism:Homo sapiens (Human)
Description:P21730
Residue:350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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  Blast E-value cutoff:
BDBM50012290
NameBDBM50012290
Synonyms:2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-6-amino-hexanoylamino}-3-carboxy-propionylamino)-4-methylsulfanyl-butyrylamino]-4-carbamoyl-butyrylamino}-4-methyl-pentanoylamino)-acetylamino]-5-guanidino-pentanoic acid(Ac-His-Lys-Asp-Met-Gln-Leu-Gly-Arg) | CHEMBL440421
TypeSmall organic molecule
Emp. Form.C42H71N15O13S
Mol. Mass.1026.171
SMILESCSCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Structure
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