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Target
Pancreatic alpha-amylase
Ligand
BDBM50182487
Substrate
n/a
Meas. Tech.
ChEMBL_1713756 (CHEMBL4123805)
IC50
19070±n/a nM
Citation
 Prabha, B; Neethu, S; Krishnan, SL; Sherin, DR; Madhukrishnan, M; Ananthakrishnan, R; Rameshkumar, KB; Manojkumar, TK; Jayamurthy, P; Radhakrishnan, KV Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem 26:3461-3467 (2018) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase
Type:
Protein
Mol. Mass.:
57088.07
Organism:
Sus scrofa (Pig)
Description:
P00690
Residue:
511
Sequence:
MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPPNENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGSGAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGLLDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAGSRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWARNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQPFANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGIKVYVSSDGTAQFSISNSAEDPFIAIHAESKL
  
Inhibitor
Name:
BDBM50182487
Synonyms:
Malabaricone A
Type:
Small organic molecule
Emp. Form.:
C21H26O3
Mol. Mass.:
326.4293
SMILES:
Oc1cccc(O)c1C(=O)CCCCCCCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: