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Target
Chymotrypsin-like elastase family member 1
Ligand
BDBM50014740
Substrate
n/a
Meas. Tech.
ChEMBL_63626 (CHEMBL675337)
Ki
41000±n/a nM
Citation
 Peet, NP; Burkhart, JP; Angelastro, MR; Giroux, EL; Mehdi, S; Bey, P; Kolb, M; Neises, B; Schirlin, D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem 33:394-407 (1990) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 1
Synonyms:
CELA1 | CELA1_HUMAN | ELA1 | Elastase 1 | Elastase-1
Type:
PROTEIN
Mol. Mass.:
27805.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_63626
Residue:
258
Sequence:
MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
  
Inhibitor
Name:
BDBM50014740
Synonyms:
Acetyl-Pro-Ala-Pro-Ala-trifluoro methane | CHEMBL130718
Type:
Small organic molecule
Emp. Form.:
C19H27F3N4O5
Mol. Mass.:
448.4367
SMILES:
C[C@H](NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)C(F)(F)F
Structure:
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