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Target
Butyrophilin subfamily 3 member A1
Ligand
BDBM50278623
Substrate
n/a
Meas. Tech.
ChEMBL_1719033 (CHEMBL4134033)
EC50
9.0±n/a nM
Citation
 Foust, BJ; Poe, MM; Lentini, NA; Hsiao, CC; Wiemer, AJ; Wiemer, DF Mixed Aryl Phosphonate Prodrugs of a Butyrophilin Ligand. ACS Med Chem Lett 8:914-918 (2017) [PubMed]  Article 
Target
Name:
Butyrophilin subfamily 3 member A1
Synonyms:
BT3A1_HUMAN | BTF5 | BTN3A1 | Butyrophilin subfamily 3 member A1 | CD_antigen=CD277
Type:
PROTEIN
Mol. Mass.:
57685.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_117363
Residue:
513
Sequence:
MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
  
Inhibitor
Name:
BDBM50278623
Synonyms:
CHEMBL4160740
Type:
Small organic molecule
Emp. Form.:
C22H29O5P
Mol. Mass.:
404.4364
SMILES:
C\C(CO)=C/CCP(=O)(COC(=O)C(C)(C)C)Oc1cccc2ccccc12
Structure:
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