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Target
Translocator protein
Ligand
BDBM50279015
Substrate
n/a
Meas. Tech.
ChEMBL_1720335 (CHEMBL4135335)
Kd
61±n/a nM
Citation
 Kim, T; Son, WS; Morshed, MN; Londhe, AM; Jung, SY; Park, JH; Park, WK; Lim, SM; Park, KD; Cho, SJ; Jeong, KS; Lee, J; Pae, AN Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against A?-induced neurotoxicity. Eur J Med Chem 141:240-256 (2017) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50279015
Synonyms:
CHEMBL4174207
Type:
Small organic molecule
Emp. Form.:
C20H20N4OS2
Mol. Mass.:
396.529
SMILES:
CCc1nnc(SCC(=O)N(C)c2ccccc2)c2cc3sc(C)cc3n12
Structure:
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