Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50017453
Substrate
n/a
Meas. Tech.
ChEBML_62229
Ki
449.0±n/a nM
Citation
 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. J Med Chem 32:1052-6 (1989) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50017453
Synonyms:
1-(2-Ethyl-phenyl)-piperazine | CHEMBL9467
Type:
Small organic molecule
Emp. Form.:
C12H18N2
Mol. Mass.:
190.2847
SMILES:
CCc1ccccc1N1CCNCC1
Structure:
Search PDB for entries with ligand similarity: