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TargetBeta-lactamase
LigandBDBM50450974
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1744439
Ki 0.200000±n/a nM
Citation González-Bello, C Antibiotic adjuvants - A strategy to unlock bacterial resistance to antibiotics. Bioorg Med Chem Lett27:4221-4228 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-lactamase
Name:Beta-lactamase
Synonyms:3.5.2.6 | Beta-lactamase | ampC
Type:PROTEIN
Mol. Mass.:75487.24
Organism:Bacillus cereus
Description:ChEMBL_117771
Residue:676
Sequence:
MKQAINKLGIVAVLLSSSTMISACSQQLLEAEKSKPLASSTNIQMMEGPNNKKEIESFAD
PLFEEKMKKYNVNGSSFVVVHDGKVVVNKGYGYANKEKKIPVTKDTVFQIASVSKTFTAL
AVMQQVDKGKLKLDQDVQKYLGGLQIPNQTGKPLTLFDMLTYTSGVDFPDLTNITGPEYV
HNSIPMKEFFSKHMPTVIRPPGEVYTYDNVSFALAGFAVENATNTPFSKYMEKNIFKPLD
MESTSMSFTPDLLKRMATHYGPTGDPIPTSGSGLRDTPQGGILSTAEDMSKYMIMQLQKG
TFKDKEIISKKGIDMMHAYQVFDDKTVPVATIGFETPFNKFANDQHVVMKGGSMPGHQSL
LILVPEQKTAFFMSYNNDSMMSIDIYEALMDHYFPAKKNEVKTSYLPLEEKEAHKYLGLF
QNTRFAAIRTHFTYENGNLIMEGGTTGKQVLKMIHSLLFEDSEGNKVAFKKNSAGEITYF
HYTSPKSLDFVADAQKINNKSPFDDVPAKSKYRSHIDNLHALNIMGAKTDNLFNPMDTMT
QGEFADMLLLAHGWNGFPDESKEAREKMINGIPEYNRATPITRQVAATMIQNVKQIQDLK
PIRPDKAIKVKLLDAADDWAVQSIQALASQGILDPDTSINADGSFMFRPKDVLLRQEASS
LLDLAFGYYSLPIKRQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50450974
NameBDBM50450974
Synonyms:CHEMBL4206040
TypeSmall organic molecule
Emp. Form.C9H9BClN5O5S
Mol. Mass.345.527
SMILESOB(O)CNC(=O)S(=O)(=O)c1cc(Cl)cc(c1)-c1nnn[nH]1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a