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Target
Glutathione S-transferase omega-1
Ligand
BDBM50458521
Substrate
n/a
Meas. Tech.
ChEMBL_1764010 (CHEMBL4199257)
IC50
900000±n/a nM
Citation
 Xie, Y; Dahlin, JL; Oakley, AJ; Casarotto, MG; Board, PG; Baell, JB Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem 61:7448-7470 (2018) [PubMed]  Article 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM50458521
Synonyms:
1-chloro-2,4-dinitrobenzene | CHEBI:34718 | Dinitrochlorobenzene | NSC-6292
Type:
Small organic molecule
Emp. Form.:
C6H3ClN2O4
Mol. Mass.:
202.552
SMILES:
[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O
Structure:
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