Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM31712
Substrate
n/a
Meas. Tech.
ChEMBL_1764058 (CHEMBL4199305)
Ki
5550±n/a nM
Citation
 Trivedi-Parmar, V; Jorgensen, WL Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor. J Med Chem 61:8104-8119 (2018) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM31712
Synonyms:
HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 | SMR000058356 | cid_3598
Type:
Small organic molecule
Emp. Form.:
C13H6Cl6O2
Mol. Mass.:
406.904
SMILES:
Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
Structure:
Search PDB for entries with ligand similarity: