Reaction Details Report a problem with these data
Target
Rhizopuspepsin
Ligand
BDBM50022289
Substrate
n/a
Meas. Tech.
ChEBML_222282
Ki
47±n/a nM
Citation
 Salituro, FG; Agarwal, N; Hofmann, T; Rich, DH Inhibition of aspartic proteinases by peptides containing lysine and ornithine side-chain analogues of statine. J Med Chem 30:286-95 (1987) [PubMed]  Article 
Target
Name:
Rhizopuspepsin
Synonyms:
CARP_RHICH | Rhizopuspepsin
Type:
PROTEIN
Mol. Mass.:
41326.43
Organism:
Rhizopus microsporus var. chinensis
Description:
ChEMBL_100244
Residue:
393
Sequence:
MKFTLISSCIAIAALAVAVDAAPGEKKISIPLAKNPNYKPSAKNAIQKAIAKYNKHKINTSTGGIVPDAGVGTVPMTDYGNDVEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTNCGSRQTKYDPKQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKGQTIELAKREAASFANGPNDGLLGLGFDTITTVRGVKTPMDNLISQGLISRPIFGVYLGKASNGGGGEYIFGGYDSTKFKGSLTTVPIDNSRGWWGITVDRATVGTSTVASSFDGILDTGTTLLILPNNVAASVARAYGASDNGDGTYTISCDTSRFKPLVFSINGASFQVSPDSLVFEEYQGQCIAGFGYGNFDFAIIGDTFLKNNYVVFNQGVPEVQIAPVAQ
  
Inhibitor
Name:
BDBM50022289
Synonyms:
Acetate6-ethoxycarbonyl-5-hydroxy-4-{3-methyl-2-[3-methyl-2-(3-methyl-butyrylamino)-butyrylamino]-butyrylamino}-hexyl-ammonium; | CHEMBL319016
Type:
Small organic molecule
Emp. Form.:
C24H47N4O6
Mol. Mass.:
487.6526
SMILES:
CCOC(=O)CC(O)[C@H](CCC[NH3+])NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Structure:
Search PDB for entries with ligand similarity: