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Target
Butyrophilin subfamily 3 member A1
Ligand
BDBM50236893
Substrate
n/a
Meas. Tech.
ChEMBL_1766264 (CHEMBL4201511)
EC50
0.510000±n/a nM
Citation
 Lentini, NA; Foust, BJ; Hsiao, CC; Wiemer, AJ; Wiemer, DF Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent V?9 V?2 T Cell Stimulation. J Med Chem 61:8658-8669 (2018) [PubMed]  Article 
Target
Name:
Butyrophilin subfamily 3 member A1
Synonyms:
BT3A1_HUMAN | BTF5 | BTN3A1 | Butyrophilin subfamily 3 member A1 | CD_antigen=CD277
Type:
PROTEIN
Mol. Mass.:
57685.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_117363
Residue:
513
Sequence:
MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
  
Inhibitor
Name:
BDBM50236893
Synonyms:
CHEBI:15664 | CHEMBL145233
Type:
Small organic molecule
Emp. Form.:
C5H12O8P2
Mol. Mass.:
262.0915
SMILES:
C\C(CO)=C/COP(O)(=O)OP(O)(O)=O
Structure:
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