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TargetProtein kinase C (PKC)
LigandBDBM50241867
Substrate/Competitorn/a
Meas. Tech.ChEMBL_505888
IC50 21000±n/a nM
Citation Herbert, JMMaffrand, JPTaoubi, KAugereau, JMFouraste, IGleye, J Verbascoside isolated from Lantana camara, an inhibitor of protein kinase C. J Nat Prod54:1595-600[PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protein kinase C (PKC)
Name:Protein kinase C (PKC)
Synonyms:Pkcz | Prkcz | Protein kinase C zeta type | nPKC-zeta
Type:PROTEIN
Mol. Mass.:67722.31
Organism:Rattus norvegicus
Description:ChEMBL_104731
Residue:592
Sequence:
MPSRTDPKMDRSGGRVRLKAHYGGDILITSVDPTTTFQDLCEEVRDMCGLHQQHPLTLKW
VDSEGDPCTVSSQMELEEAFRLACQGRDEVLIIHVFPSIPEQPGMPCPGEDKSIYRRGAR
RWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHVLVPLTC
RRHMDSVMPSQEPPVDDKNDGVDLPSEETDGIAYISSSRKHDNIKDDSEDLKPVIDGVDG
IKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTE
KHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEI
CIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP
EILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF
LSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQIT
DDYGLDNFDTQFTSEPVQLTPDDEDVIKRIDQSEFEGFEYINPLLLSAEESV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50241867
NameBDBM50241867
Synonyms:((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl) 3-(3,4-dihydroxyphenyl)acrylate | ((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl)3-(3,4-dihydroxyphenyl)acrylate | ACETOSIDE | CHEMBL231853 | cid_24978601 | cid_5281800 | verbacoside | verbascoside
TypeSmall organic molecule
Emp. Form.C29H36O15
Mol. Mass.624.5871
SMILESC[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O |r|
Structure
n/a