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Target
Adenosine receptor A1
Ligand
BDBM50025683
Substrate
n/a
Meas. Tech.
ChEBML_29624
Ki
140±n/a nM
Citation
 Jacobson, KA; Ukena, D; Padgett, W; Daly, JW; Kirk, KL Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. J Med Chem 30:211-4 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50025683
Synonyms:
CHEMBL307313 | Propionic acid 4-(1,3-diethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxymethyl ester
Type:
Small organic molecule
Emp. Form.:
C19H22N4O5
Mol. Mass.:
386.4018
SMILES:
CCC(=O)OCOc1ccc(cc1)-c1nc2n(CC)c(=O)n(CC)c(=O)c2[nH]1
Structure:
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