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Target
Chymotrypsin-like elastase family member 1/2A
Ligand
BDBM50225470
Substrate
n/a
Meas. Tech.
ChEMBL_152334 (CHEMBL758716)
Ki
2410000±n/a nM
Citation
 Groutas, WC; Abrams, WR; Theodorakis, MC; Kasper, AM; Rude, SA; Badger, RC; Ocain, TD; Miller, KE; Moi, MK; Brubaker, MJ Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase. J Med Chem 28:204-9 (1985) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 1/2A
Synonyms:
Pancreatic elastase
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of ChEMBL is 152345
Components:
This complex has 2 components.
Component 1
Name:
Chymotrypsin-like elastase family member 1
Synonyms:
CELA1 | CELA1_PIG | ELA1 | Elastase | Elastase 1 | Elastase-1 | Pancreatic elastase
Type:
Enzyme
Mol. Mass.:
28827.71
Organism:
Sus scrofa (Pig)
Description:
P00772
Residue:
266
Sequence:
MLRLLVVASLVLYGHSTQDFPETNARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
  
Component 2
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50225470
Synonyms:
CHEMBL294543
Type:
Small organic molecule
Emp. Form.:
C9H15N3O
Mol. Mass.:
181.2349
SMILES:
CCCCNC(=O)n1ccnc1C
Structure:
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