Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50467925
Substrate
n/a
Meas. Tech.
ChEMBL_1797350 (CHEMBL4269467)
Ki
10.0±n/a nM
Citation
 Gadhiya, S; Cordone, P; Pal, RK; Gallicchio, E; Wickstrom, L; Kurtzman, T; Ramsey, S; Harding, WW New Dopamine D3-Selective Receptor Ligands Containing a 6-Methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol Motif. ACS Med Chem Lett 9:990-995 (2018) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50467925
Synonyms:
CHEMBL4280542
Type:
Small organic molecule
Emp. Form.:
C21H25IN2O3
Mol. Mass.:
480.3393
SMILES:
COc1cc2CCN(CCCCNC(=O)c3ccc(I)cc3)Cc2cc1O
Structure:
Search PDB for entries with ligand similarity: