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Target
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Ligand
BDBM50015358
Substrate
n/a
Meas. Tech.
ChEBML_159843
Ki
90±n/a nM
Citation
 Bey, P; Bolkenius, FN; Seiler, N; Casara, P N-2,3-Butadienyl-1,4-butanediamine derivatives: potent irreversible inactivators of mammalian polyamine oxidase. J Med Chem 28:1-2 (1985) [PubMed]  Article 
Target
Name:
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Synonyms:
Acetylpolyamine oxidase (APAO) | PAO | PAOX | PAOX_HUMAN | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Polyamine oxidase
Type:
Enzyme
Mol. Mass.:
70274.33
Organism:
Homo sapiens (Human)
Description:
Q6QHF9
Residue:
649
Sequence:
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGTSVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVARLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL
  
Inhibitor
Name:
BDBM50015358
Synonyms:
CHEMBL417844 | N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE | N,N'-Di-buta-2,3-dienyl-butane-1,4-diamine
Type:
Small organic molecule
Emp. Form.:
C12H20N2
Mol. Mass.:
192.3006
SMILES:
C=C=CCNCCCCNCC=C=C
Structure:
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