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Target
Phospholipase A1 member A
Ligand
BDBM50470660
Substrate
n/a
Meas. Tech.
ChEMBL_155873 (CHEMBL769592)
IC50
91400±n/a nM
Citation
 Kotretsou, S; Mingeot-Leclercq, MP; Constantinou-Kokotou, V; Brasseur, R; Georgiadis, MP; Tulkens, PM Synthesis and antimicrobial and toxicological studies of amino acid and peptide derivatives of kanamycin A and netilmicin. J Med Chem 38:4710-9 (1995) [PubMed]  Article 
Target
Name:
Phospholipase A1 member A
Synonyms:
3.1.1.- | PLA1A_RAT | PS-PLA1 | Phosphatidylserine-specific phospholipase A1 | Phospholipase A1 member A | Pla1a | Pspla1
Type:
PROTEIN
Mol. Mass.:
50213.12
Organism:
Rattus norvegicus
Description:
ChEMBL_12251
Residue:
456
Sequence:
MCPGLWGTCFWLWGSLLWLSIGRSGNVPPTTQPKCTDFQSANLLRGTNLKVQFLLFTPSDPGCGQLVEEDSDIRNSEFNASLGTKLIIHGFRALGTKPSWINKFIRALLRAADANVIAVDWVYGSTGMYFSAVENVVKLSLEISRFLSKLLELGVSESSIHIIGVSLGAHVGGMVGHFYKGQLGRITGLDPAGPEYTRASLEERLDSGDALFVEAIHTDTDNLGIRIPVGHVDYFVNGGQDQPGCPAFIHAGYSYLICDHMRAVHLYISALENTCPLMAFPCASYKAFLAGDCLDCFNPFLLSCPRIGLVERGGVKIEPLPKEVRVYLQTTSSAPYCVHHSLVEFNLKEKRKKDTSIEVTFLGNNVTSSVKITIPKDHLEGRGIIAHQNPHCQINQVKLKFHISSRVWRKDRTPIVGTFCTAPLPVNDSKKTVCIPEPVRLQVSMAVLRDLKMACV
  
Inhibitor
Name:
BDBM50470660
Synonyms:
CHEMBL142949
Type:
Small organic molecule
Emp. Form.:
C24H46N6O8
Mol. Mass.:
546.6574
SMILES:
CCNC1CC(N)C(OC2OC(CNC(=O)C(C)N)=CCC2N)C(O)C1OC1OCC(C)(O)C(NC)C1O |c:18|
Structure:
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