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Target
Protein kinase C zeta type
Ligand
BDBM50471336
Substrate
n/a
Meas. Tech.
ChEMBL_162376 (CHEMBL767464)
IC50
>10000±n/a nM
Citation
 Hudkins, RL; Diebold, JL; Angeles, TS; Knight, E Fused pyrrolo[2,3-c]carbazol-6-ones: novel immunostimulants that enhance human interferon-gamma activity. J Med Chem 40:2994-6 (1997) [PubMed]  Article 
Target
Name:
Protein kinase C zeta type
Synonyms:
KPCZ_RAT | Pkcz | Prkcz | Protein kinase C (PKC) | Protein kinase C zeta type | nPKC-zeta
Type:
PROTEIN
Mol. Mass.:
67722.31
Organism:
Rattus norvegicus
Description:
ChEMBL_104731
Residue:
592
Sequence:
MPSRTDPKMDRSGGRVRLKAHYGGDILITSVDPTTTFQDLCEEVRDMCGLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLACQGRDEVLIIHVFPSIPEQPGMPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHVLVPLTCRRHMDSVMPSQEPPVDDKNDGVDLPSEETDGIAYISSSRKHDNIKDDSEDLKPVIDGVDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDVIKRIDQSEFEGFEYINPLLLSAEESV
  
Inhibitor
Name:
BDBM50471336
Synonyms:
CHEMBL419726
Type:
Small organic molecule
Emp. Form.:
C20H12N2OS
Mol. Mass.:
328.387
SMILES:
O=C1Cc2c(N1)c1c3ccccc3sc1c1[nH]c3ccccc3c21
Structure:
Search PDB for entries with ligand similarity: