Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50064259
Substrate
n/a
Meas. Tech.
ChEMBL_211479 (CHEMBL819682)
IC50
>80000±n/a nM
Citation
 Pettit, GR; Toki, B; Herald, DL; Verdier-Pinard, P; Boyd, MR; Hamel, E; Pettit, RK Antineoplastic agents. 379. Synthesis of phenstatin phosphate. J Med Chem 41:1688-95 (1998) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50064259
Synonyms:
CHEMBL289351 | Combretastatin A4 phosphate | Di-Sodium salt of Phosphoric acid mono-{2-methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl} ester | Disodium Phosphoric acid mono-{2-methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl} ester | Phosphoric acid mono-{2-methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl} ester; disodium salt | combretastatin A-4 phosphate | combretastatin A-4 sodium phosphate | disodium 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenyl phosphate | disodium mono(Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenyl phosphate | sodium (Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenyl phosphate | sodium(Z)-2-methoxy-5-(3,4,5-trimethoxystyryl)phenyl phosphate
Type:
Small organic molecule
Emp. Form.:
C18H19O8P
Mol. Mass.:
394.3135
SMILES:
COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1OP([O-])([O-])=O
Structure:
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