Reaction Details Report a problem with these data
Target
Beta-3 adrenergic receptor
Ligand
BDBM82487
Substrate
n/a
Meas. Tech.
ChEMBL_39067 (CHEMBL651138)
Ki
21±n/a nM
Citation
 Zheng, W; Nikulin, VI; Konkar, AA; Vansal, SS; Shams, G; Feller, DR; Miller, DD 2-Amino-4-benzyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridines: novel selective beta3-adrenoceptor agonists. J Med Chem 42:2287-94 (1999) [PubMed]  Article 
Target
Name:
Beta-3 adrenergic receptor
Synonyms:
ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
43534.88
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
408
Sequence:
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
  
Inhibitor
Name:
BDBM82487
Synonyms:
TMQ, 3',5'-Diiodo
Type:
Small organic molecule
Emp. Form.:
C17H17I2NO3
Mol. Mass.:
537.1307
SMILES:
COc1c(I)cc(CC2NCCc3cc(O)c(O)cc23)cc1I
Structure:
Search PDB for entries with ligand similarity: