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Target
Leukotriene B4 receptor 2
Ligand
BDBM50472431
Substrate
n/a
Meas. Tech.
ChEMBL_99657 (CHEMBL704423)
IC50
7000±n/a nM
Citation
 Poudrel, JM; Hullot, P; Vidal, JP; Girard, JP; Rossi, JC; Muller, A; Bonne, C; Bezuglov, V; Serkov, I; Renard, P; Pfeiffer, B Synthesis and structure-activity relationships of new 1, 3-disubstituted cyclohexanes as structurally rigid leukotriene B(4) receptor antagonists. J Med Chem 42:5289-310 (1999) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 2
Synonyms:
BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37964.86
Organism:
Homo sapiens (Human)
Description:
Leukotriene 2 0 HUMAN::Q9NPC1
Residue:
358
Sequence:
MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
Inhibitor
Name:
BDBM50472431
Synonyms:
CHEMBL264039
Type:
Small organic molecule
Emp. Form.:
C23H33NO3
Mol. Mass.:
371.513
SMILES:
CN(C)OC(=O)\C=C1\CCC[C@@H](C1)\C=C\C(O)CCCCc1ccccc1
Structure:
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