Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50027288
Substrate
n/a
Meas. Tech.
ChEBML_212516
Ki
2960±n/a nM
Citation
 Tidwell, RR; Geratz, JD; Dubovi, EJ Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin. J Med Chem 26:294-8 (1983) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50027288
Synonyms:
2-{4-[3-(4-Carbamimidoyl-phenoxy)-propoxy]-phenyl}-1H-benzoimidazole-5-carboxamidine | CHEMBL102148
Type:
Small organic molecule
Emp. Form.:
C24H24N6O2
Mol. Mass.:
428.4864
SMILES:
NC(=N)c1ccc(OCCCOc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(N)=N)cc1
Structure:
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