Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 2
Ligand
BDBM50476610
Substrate
n/a
Meas. Tech.
ChEMBL_444217 (CHEMBL893371)
IC50
1900±n/a nM
Citation
 Junek, R; Br?nová, B; Kverka, M; Panajotová, V; Jandera, A; Kuchar, M Antileukotrienic N-arylethyl-2-arylacetamides in the treatment of ulcerative colitis. Eur J Med Chem 42:1084-94 (2007) [PubMed]  Article 
Target
Name:
Leukotriene B4 receptor 2
Synonyms:
BLT2R | BLTR2 | LT4R2_HUMAN | LTB4 receptor JULF2 | LTB4-R 2 | LTB4-R2 | LTB4R2 | LTB4R2 protein | Leukotriene B4 | Leukotriene B4 R2 | Leukotriene B4 receptor | Leukotriene B4 receptor 2 | Leukotriene B4 receptor BLT2 | Leukotriene b1 | Seven transmembrane receptor BLTR2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37964.86
Organism:
Homo sapiens (Human)
Description:
Leukotriene 2 0 HUMAN::Q9NPC1
Residue:
358
Sequence:
MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
  
Inhibitor
Name:
BDBM50476610
Synonyms:
CHEMBL390870
Type:
Small organic molecule
Emp. Form.:
C30H34BrNO6
Mol. Mass.:
584.498
SMILES:
COc1cc(CC(O)=O)ccc1OCCCCOc1ccc(CC(=O)N(C)CCc2ccc(Br)cc2)cc1
Structure:
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