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Target
Melatonin receptor type 1C
Ligand
BDBM50476621
Substrate
n/a
Meas. Tech.
ChEMBL_444320 (CHEMBL893556)
EC50
46±n/a nM
Citation
 Faust, R; Garratt, PJ; Trujillo Pérez, MA; Piccio, VJ; Madsen, C; Stenstrĝm, A; Frĝlund, B; Davidson, K; Teh, MT; Sugden, D 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorg Med Chem 15:4543-51 (2007) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1C
Synonyms:
MTR1C_XENLA | Melatonin 1C | Melatonin receptor 1C | Melatonin receptor type 1C | mtnr1c
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47442.40
Organism:
Xenopus
Description:
Melatonin 1C 0 Xenopus::P49219
Residue:
420
Sequence:
MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
  
Inhibitor
Name:
BDBM50476621
Synonyms:
CHEMBL394408
Type:
Small organic molecule
Emp. Form.:
C21H24N2O2
Mol. Mass.:
336.4275
SMILES:
CCCC(=O)NCCc1c[nH]c2c(cc(OC)cc12)-c1ccccc1
Structure:
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