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TargetReverse transcriptase
LigandBDBM50377911
Substrate/Competitorn/a
Meas. Tech.ChEMBL_487140
EC50 31700±n/a nM
Citation Chen, KShi, QKashiwada, YZhang, DCHu, CQJin, JQNozaki, HKilkuskie, RETramontano, ECheng, YC Anti-aids agents, 6. Salaspermic acid, an anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds. J Nat Prod55:340-6 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Reverse transcriptase
Name:Reverse transcriptase
Synonyms:n/a
Type:Protein
Mol. Mass.:29598.37
Organism:Human immunodeficiency virus 1
Description:Q9WKE8
Residue:254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50377911
NameBDBM50377911
Synonyms:CHEMBL483649
TypeSmall organic molecule
Emp. Form.C30H48O4
Mol. Mass.472.6997
SMILESC[C@H]1[C@@]2(O)CC[C@@H]3[C@]1(CO2)CC[C@H]1[C@@]3(C)CC[C@@]2(C)[C@@H]3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(O)=O |r|
Structure
n/a