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Target
Cytochrome P450 11B1, mitochondrial
Ligand
BDBM50028164
Substrate
n/a
Meas. Tech.
ChEBML_192
IC50
87470±n/a nM
Citation
 Hays, SJ; Tobes, MC; Gildersleeve, DL; Wieland, DM; Beierwaltes, WH Structure-activity relationship study of the inhibition of adrenal cortical 11 beta-hydroxylase by new metyrapone analogues. J Med Chem 27:15-9 (1984) [PubMed]  Article 
Target
Name:
Cytochrome P450 11B1, mitochondrial
Synonyms:
C11B1_BOVIN | CYP11B1 | Cytochrome P450 11B1
Type:
PROTEIN
Mol. Mass.:
57863.81
Organism:
Bos taurus
Description:
ChEMBL_1345884
Residue:
503
Sequence:
MALWAKARVRMAGPWLSLHEARLLGTRGAAAPKAVLPFEAMPRCPGNKWMRMLQIWKEQSSENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQADSHHPQRMILEPWLAYRQARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNARGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMLKSTVQLMFVPRRLSRWMSTNMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMTLDTIKANTIDLTAGSVDTTAFPLLMTLFELARNPEVQQAVRQESLVAEARISENPQRAITELPLLRAALKETLRLYPVGITLEREVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARPESYHPQRWLDRQGSGSRFPHLAFGFGVRQCLGRRVAEVEMLLLLHHVLKNFLVETLEQEDIKMVYRFILMPSTLPLFTFRAIQ
  
Inhibitor
Name:
BDBM50028164
Synonyms:
CHEMBL57308 | N-(2-Methyl-1,2-di-pyridin-3-yl-propyl)-acetamide
Type:
Small organic molecule
Emp. Form.:
C16H19N3O
Mol. Mass.:
269.3416
SMILES:
CC(=O)NC(c1cccnc1)C(C)(C)c1cccnc1
Structure:
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