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Target
Reverse transcriptase
Ligand
BDBM50480249
Substrate
n/a
Meas. Tech.
ChEMBL_545151 (CHEMBL1018093)
IC50
>193000±n/a nM
Citation
 Tan, GT; Pezzuto, JM; Kinghorn, AD; Hughes, SH Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J Nat Prod 54:143-54[PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50480249
Synonyms:
CHEBI:9630 | Tomatine
Type:
Small organic molecule
Emp. Form.:
C50H83NO21
Mol. Mass.:
1034.1881
SMILES:
[H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@]1(CC[C@H](C)CN1)O2)O[C@]1([H])O[C@H](CO)[C@]([H])(O[C@@H]2O[C@H](CO)[C@@H](O)[C@]([H])(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@@]2([H])O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r|
Structure:
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