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Target
Reverse transcriptase
Ligand
BDBM50480320
Substrate
n/a
Meas. Tech.
ChEMBL_545151 (CHEMBL1018093)
IC50
>567000±n/a nM
Citation
 Tan, GT; Pezzuto, JM; Kinghorn, AD; Hughes, SH Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. J Nat Prod 54:143-54[PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50480320
Synonyms:
CHEMBL519833 | Iso-Schizogamine
Type:
Small organic molecule
Emp. Form.:
C21H24N2O3
Mol. Mass.:
352.4269
SMILES:
[H][C@@]12CC[C@]34CC(=O)N5c6cc(OC)c(OC)cc6[C@]1([H])CCN(CC=C3)C245 |r,c:27,TLB:2:1:18.9.8:21.22.23|
Structure:
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