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Target
Alpha-tocopherol transfer protein
Ligand
BDBM50458513
Substrate
n/a
Meas. Tech.
ChEMBL_605568 (CHEMBL1069214)
Kd
2420±n/a nM
Citation
 López, GV; Gómez, LE; Campillo, N; Páez, JA; Giles, K; Atkinson, J; González, M; Rubbo, H; Cerecetto, H Interaction studies between human alpha-tocopherol transfer protein and nitric oxide donor tocopherol analogues with LDL-protective activity. Bioorg Med Chem 17:8143-8 (2009) [PubMed]  Article 
Target
Name:
Alpha-tocopherol transfer protein
Synonyms:
Alpha-TTP | Alpha-tocopherol transfer protein | TPP1 | TTPA | TTPA_HUMAN
Type:
PROTEIN
Mol. Mass.:
31754.31
Organism:
Homo sapiens
Description:
ChEMBL_109106
Residue:
278
Sequence:
MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
  
Inhibitor
Name:
BDBM50458513
Synonyms:
Alpha Tocopherol | Aquasol E | CHEBI:18145 | E307 | Tocopherol | Vitamin E
Type:
Small organic molecule
Emp. Form.:
C29H50O2
Mol. Mass.:
430.7061
SMILES:
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1 |r|
Structure:
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