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Target
Reverse transcriptase
Ligand
BDBM50483429
Substrate
n/a
Meas. Tech.
ChEMBL_718270 (CHEMBL1679574)
Kd
30000±n/a nM
Citation
 Brandt, P; Geitmann, M; Danielson, UH Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments. J Med Chem 54:709-18 (2011) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50483429
Synonyms:
CHEMBL1535399
Type:
Small organic molecule
Emp. Form.:
C14H13ClN2O4S
Mol. Mass.:
340.782
SMILES:
NS(=O)(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1
Structure:
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