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Target
Reverse transcriptase
Ligand
BDBM2182
Substrate
n/a
Meas. Tech.
ChEMBL_758401 (CHEMBL1811267)
IC50
7180±n/a nM
Citation
 Bode, ML; Gravestock, D; Moleele, SS; van der Westhuyzen, CW; Pelly, SC; Steenkamp, PA; Hoppe, HC; Khan, T; Nkabinde, LA Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors. Bioorg Med Chem 19:4227-37 (2011) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM2182
Synonyms:
SM29 | US8501787, 165
Type:
n/a
Emp. Form.:
C20H22ClN3
Mol. Mass.:
339.862
SMILES:
Cc1cccn2c(NC3CCCCC3)c(nc12)-c1ccccc1Cl
Structure:
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