Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50009868
Substrate
n/a
Meas. Tech.
ChEMBL_46624 (CHEMBL658880)
IC50
390±n/a nM
Citation
 Eissenstat, MA; Bell, MR; D'Ambra, TE; Alexander, EJ; Daum, SJ; Ackerman, JH; Gruett, MD; Kumar, V; Estep, KG; Olefirowicz, EM Aminoalkylindoles: structure-activity relationships of novel cannabinoid mimetics. J Med Chem 38:3094-105 (1995) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50009868
Synonyms:
(4-Methoxy-phenyl)-[1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | (s-trans)-(4-Methoxy-phenyl)-[1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone | CHEMBL273606
Type:
Small organic molecule
Emp. Form.:
C22H24N2O3
Mol. Mass.:
364.4376
SMILES:
COc1ccc(cc1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Structure:
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