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Target
Retinoic acid receptor RXR-beta
Ligand
BDBM50032677
Substrate
n/a
Meas. Tech.
ChEMBL_197061 (CHEMBL807508)
EC50
310±n/a nM
Citation
 Boehm, MF; Zhang, L; Zhi, L; McClurg, MR; Berger, E; Wagoner, M; Mais, DE; Suto, CM; Davies, JA; Heyman, RA Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells. J Med Chem 38:3146-55 (1995) [PubMed]  Article 
Target
Name:
Retinoic acid receptor RXR-beta
Synonyms:
Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb
Type:
PROTEIN
Mol. Mass.:
55877.78
Organism:
Mus musculus
Description:
ChEMBL_196588
Residue:
520
Sequence:
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
  
Inhibitor
Name:
BDBM50032677
Synonyms:
4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-ethyl]-benzoic acid | CHEMBL105979
Type:
Small organic molecule
Emp. Form.:
C24H30O2
Mol. Mass.:
350.4938
SMILES:
CC(c1ccc(cc1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C
Structure:
Search PDB for entries with ligand similarity: