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Target
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic
Ligand
BDBM50153713
Substrate
n/a
Meas. Tech.
ChEMBL_925784 (CHEMBL3069077)
IC50
100±n/a nM
Citation
 Witschel, M; Röhl, F; Niggeweg, R; Newton, T In search of new herbicidal inhibitors of the non-mevalonate pathway. Pest Manag Sci 69:559-63 (2013) [PubMed]  Article 
Target
Name:
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic
Synonyms:
1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic | 1-deoxyxylulose-5-phosphate reductoisomerase | 1.1.1.267 | 2-C-methyl-D-erythritol 4-phosphate synthase | DXP reductoisomerase | DXR | DXR_ARATH | ISPC | PDE129 | PDE129 | Protein PIGMENT-DEFECTIVE EMBRYO 129
Type:
PROTEIN
Mol. Mass.:
51966.29
Organism:
Arabidopsis thaliana
Description:
ChEMBL_105556
Residue:
477
Sequence:
MMTLNSLSPAESKAISFLDTSRFNPIPKLSGGFSLRRRNQGRGFGKGVKCSVKVQQQQQPPPAWPGRAVPEAPRQSWDGPKPISIVGSTGSIGTQTLDIVAENPDKFRVVALAAGSNVTLLADQVRRFKPALVAVRNESLINELKEALADLDYKLEIIPGEQGVIEVARHPEAVTVVTGIVGCAGLKPTVAAIEAGKDIALANKETLIAGGPFVLPLANKHNVKILPADSEHSAIFQCIQGLPEGALRKIILTASGGAFRDWPVEKLKEVKVADALKHPNWNMGKKITVDSATLFNKGLEVIEAHYLFGAEYDDIEIVIHPQSIIHSMIETQDSSVLAQLGWPDMRLPILYTMSWPDRVPCSEVTWPRLDLCKLGSLTFKKPDNVKYPSMDLAYAAGRAGGTMTGVLSAANEKAVEMFIDEKISYLDIFKVVELTCDKHRNELVTSPSLEEIVHYDLWAREYAANVQLSSGARPVHA
  
Inhibitor
Name:
BDBM50153713
Synonyms:
3-(N-hydroxyformamido)propylphosphonic acid | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | CHEMBL203125 | [3-(Formyl-hydroxy-amino)-propyl]-phosphonic acid | fosmidomycin
Type:
Small organic molecule
Emp. Form.:
C4H10NO5P
Mol. Mass.:
183.0997
SMILES:
ON(CCCP(O)(O)=O)C=O
Structure:
Search PDB for entries with ligand similarity: