Reaction Details Report a problem with these data
Target
Muscarinic receptor M1
Ligand
BDBM50034872
Substrate
n/a
Meas. Tech.
ChEMBL_138130 (CHEMBL872660)
Ki
0.20±n/a nM
Citation
 Kiesewetter, DO; Silverton, JV; Eckelman, WC Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates. J Med Chem 38:1711-9 (1995) [PubMed]  Article 
Target
Name:
Muscarinic receptor M1
Synonyms:
Muscarinic acetylcholine receptor M1
Type:
PROTEIN
Mol. Mass.:
15022.43
Organism:
Bos taurus
Description:
ChEMBL_140161
Residue:
139
Sequence:
ETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRTPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPRSSPNTVKRPTRKGRERAGKGQKPRGKEQLAKR
  
Inhibitor
Name:
BDBM50034872
Synonyms:
(S)-[4-(3-Fluoro-propyl)-phenyl]-hydroxy-phenyl-acetic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester | CHEMBL296895
Type:
Small organic molecule
Emp. Form.:
C24H28FNO3
Mol. Mass.:
397.4824
SMILES:
O[C@@](C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccc(CCCF)cc1 |wU:1.1,wD:1.0,THB:4:5:9.8:11.12,(6.11,-5.14,;5.36,-6.48,;6.88,-7.04,;7.13,-8.54,;8.06,-6.06,;9.51,-6.59,;10.28,-5.37,;11.98,-4.6,;13.54,-5.53,;12.74,-6.67,;11.14,-5.72,;11.14,-4.34,;11.98,-3.53,;4.02,-5.71,;4.02,-4.15,;2.67,-3.38,;1.36,-4.17,;1.36,-5.71,;2.67,-6.48,;4.57,-7.81,;5.3,-9.12,;4.53,-10.44,;2.99,-10.44,;2.19,-11.77,;.65,-11.75,;-.12,-13.07,;-1.66,-13.06,;2.22,-9.09,;3.03,-7.77,)|
Structure:
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