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TargetSerotonin (5-HT) receptor
LigandBDBM50035058
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1192
Ki 1000±n/a nM
Citation Kuipers, Wvan Wijngaarden, IKruse, CGter Horst-van Amstel, MTulp, MTIJzerman, AP N4-unsubstituted N1-arylpiperazines as high-affinity 5-HT1A receptor ligands. J Med Chem38:1942-54 (1995) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serotonin (5-HT) receptor
Name:Serotonin 1 (5-HT1) receptor
Synonyms:5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | G-21 | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:46445.29
Organism:Rattus norvegicus (rat)
Description:Binding assays were performed using rat hippocampal membranes.
Residue:422
Sequence:
MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGT
SLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGN
SKEHLPLPSESGSNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RR
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BDBM50035058
NameBDBM50035058
Synonyms:1-(2,3-Dimethoxy-phenyl)-piperazine | CHEMBL58963
TypeSmall organic molecule
Emp. Form.C12H18N2O2
Mol. Mass.222.2835
SMILESCOc1cccc(N2CCNCC2)c1OC
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a