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Target
D(3) dopamine receptor
Ligand
BDBM50035330
Substrate
n/a
Meas. Tech.
ChEMBL_62762 (CHEMBL676289)
Ki
30±n/a nM
Citation
 Stjernlöf, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikström, H Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 1. Effects of substituents in the aromatic system on serotonin and dopamine receptor subtypes. J Med Chem 38:2202-16 (1995) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50035330
Synonyms:
CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine | R-(+)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Type:
Small organic molecule
Emp. Form.:
C18H26N2
Mol. Mass.:
270.4124
SMILES:
CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1
Structure:
Search PDB for entries with ligand similarity: