Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 2
Ligand
BDBM50037569
Substrate
n/a
Meas. Tech.
ChEMBL_143663 (CHEMBL755904)
Ki
1.2±n/a nM
Citation
 Gicquel, S; Mazarguil, H; Desprat, C; Allard, M; Devillers, JP; Simonnet, G; Zajac, JM Structure-activity study of neuropeptide FF: contribution of N-terminal regions to affinity and activity. J Med Chem 37:3477-81 (1994) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | Gpr74 | NPFF2_RAT | Neuropeptide G-protein coupled receptor | Npff2 | Npffr2 | Npgpr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47725.66
Organism:
RAT
Description:
NPFF2 0 RAT::Q9EQD2
Residue:
417
Sequence:
MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
  
Inhibitor
Name:
BDBM50037569
Synonyms:
2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoic acid (1-{3-carbamoyl-1-[({3-carbamoyl-1-[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-propylcarbamoyl}-methyl)-carbamoyl]-propylcarbamoyl}-2-phenyl-ethyl)-amide | CHEMBL407343
Type:
Small organic molecule
Emp. Form.:
C51H72N14O10
Mol. Mass.:
1041.2052
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
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