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Reaction Details
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TargetLTB4R
LigandBDBM50039472
Substrate/Competitorn/a
Meas. Tech.ChEMBL_99656
IC50 4.5±n/a nM
Citation Harper, RWJackson, WTFroelich, LLBoyd, RJAldridge, TEHerron, DK Leukotriene B4 (LTB4) receptor antagonists: a series of (hydroxyphenyl)pyrazoles. J Med Chem37:2411-20 (1994) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
LTB4R
Name:Leukotriene B4 receptor
Synonyms:Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | LTB4-R 1 | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2Y purinoceptor 7 | P2Y7
Type:Enzyme Catalytic Domain
Mol. Mass.:37582.68
Organism:Homo sapiens (Human)
Description:Leukotriene B4 R1 LTB4R HUMAN::Q15722
Residue:352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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  Blast E-value cutoff:
BDBM50039472
NameBDBM50039472
Synonyms:7-{3-[2-Ethyl-5-hydroxy-4-(1H-pyrazol-3-yl)-phenoxy]-propoxy}-8-propyl-chroman-2-carboxylic acid | CHEMBL81401
TypeSmall organic molecule
Emp. Form.C27H32N2O6
Mol. Mass.480.5528
SMILESCCCc1c(OCCCOc2cc(O)c(cc2CC)-c2cc[nH]n2)ccc2CCC(Oc12)C(O)=O
Structure
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