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Target
Delta-type opioid receptor
Ligand
BDBM50493714
Substrate
n/a
Meas. Tech.
ChEMBL_988384 (CHEMBL2437811)
Ki
0.267000±n/a nM
Citation
 Loriga, G; Lazzari, P; Ruiu, S; Marchese, G; Manca, I; Casu, GL; Dessė, C; Pinna, GA; Asproni, B; Murineddu, G Synthesis and biological evaluation of novel delta (?) opioid receptor ligands with diazatricyclodecane skeletons. Eur J Med Chem 69:413-26 (2013) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50493714
Synonyms:
CHEMBL2436056
Type:
Small organic molecule
Emp. Form.:
C29H37N3O2
Mol. Mass.:
459.623
SMILES:
CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCC3C1CCC2N3CC=C)c1cccc(O)c1 |TLB:13:14:16.17:22.23,13:14:20.21:18.23,17:18:14.15:20.21,24:23:14.19:16.17,THB:16:15:20.21:18.23,20:19:16.17:22.23,21:22:14.19:16.17,23:18:14:20.21.22,23:22:14:16.17.18,24:23:14.15:20.21|
Structure:
Search PDB for entries with ligand similarity: