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Target
Mu-type opioid receptor
Ligand
BDBM50493758
Substrate
n/a
Meas. Tech.
ChEMBL_987443 (CHEMBL2438617)
Ki
0.120000±n/a nM
Citation
 Váradi, A; Hosztafi, S; Le Rouzic, V; Tóth, G; Urai, Á; Noszál, B; Pasternak, GW; Grinnell, SG; Majumdar, S Novel 6?-acylaminomorphinans with analgesic activity. Eur J Med Chem 69:786-9 (2013) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50493758
Synonyms:
CHEMBL2437067
Type:
Small organic molecule
Emp. Form.:
C26H25N3O5
Mol. Mass.:
459.4938
SMILES:
[H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5([H])C=C[C@H]2NC(=O)\C=C\c1cccc(c1)[N+]([O-])=O)ccc3O |r,c:19,THB:10:9:6.4.5:14|
Structure:
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