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Target
cAMP-dependent protein kinase
Ligand
BDBM50040920
Substrate
n/a
Meas. Tech.
ChEMBL_152945 (CHEMBL874643)
IC50
>500000±n/a nM
Citation
 Trinks, U; Buchdunger, E; Furet, P; Kump, W; Mett, H; Meyer, T; Müller, M; Regenass, U; Rihs, G; Lydon, N Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase. J Med Chem 37:1015-27 (1994) [PubMed]  Article 
Target
Name:
cAMP-dependent protein kinase
Synonyms:
Cyclic AMP-dependent protein kinase (PKA) | PKA catalytic subunit alpha | Serine/threonine-protein kinase | cAMP-dependent protein kinase alpha-catalytic subunit
Type:
Enzyme
Mol. Mass.:
40766.33
Organism:
Oryctolagus cuniculus (Rabbit)
Description:
Q95J97
Residue:
351
Sequence:
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAQLDQFERIKTLGTGSFGRVMLSKHKETGNHYAMKILDKQKVVKLKQIEHTLNVKRILQAVNFPFLVKLEFSFKENSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQQTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAADYPPFFADQPIQIYEKIVYGKVRFPSHFSSDLKDLLRNLQQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
  
Inhibitor
Name:
BDBM50040920
Synonyms:
5,6-Bis-p-tolylamino-isoindole-1,3-dione | CHEMBL7914
Type:
Small organic molecule
Emp. Form.:
C22H19N3O2
Mol. Mass.:
357.4052
SMILES:
Cc1ccc(Nc2cc3C(=O)NC(=O)c3cc2Nc2ccc(C)cc2)cc1
Structure:
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