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Target
Amiloride-sensitive amine oxidase [copper-containing]
Ligand
BDBM50046192
Substrate
n/a
Meas. Tech.
ChEBML_53893
IC50
1660±n/a nM
Citation
 Stanek, J; Caravatti, G; Capraro, HG; Furet, P; Mett, H; Schneider, P; Regenass, U S-adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone). J Med Chem 36:46-54 (1993) [PubMed]  Article 
Target
Name:
Amiloride-sensitive amine oxidase [copper-containing]
Synonyms:
ABP | AOC1_RAT | Abp1 | Amiloride-binding protein | Aoc1 | DAO | Diamine oxidase | Histaminase
Type:
PROTEIN
Mol. Mass.:
85028.72
Organism:
Rattus norvegicus
Description:
ChEMBL_53893
Residue:
746
Sequence:
MCLAFGWAAVILVLQTVDTASAVRTPYDKARVFADLSPQEIKAVHSFLMNREELGLQPSKEPTLAKNSVFLIEMLLPKKKHVLKFLDEGRKGPNREARAVIFFGAQDYPNVTEFAVGPLPRPYYIRALSPRPGHHLSWSSRPISTAEYDLLYHTLKRATMPLHQFFLDTTGFSFLGCDDRCLTFTDVAPRGVASGQRRSWFIVQRYVEGYFLHPTGLEILLDHGSTDVQDWRVEQLWYNGKFYNNPEELARKYAVGEVDTVVLEDPLPNGTEKPPLFSSYKPRGEFHTPVNVAGPHVVQPSGPRYKLEGNTVLYGGWSFSYRLRSSSGLQIFNVLFGGERVAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGSVTHELAPGIDCPETATFLDAFHYYDSDGPVHYPHALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGYVLVLRTTSTVYNYDYIWDFIFYSNGVMEAKMHATGYVHATFYTPEGLRHGTRLQTHLLGNIHTHLVHYRVDMDVAGTKNSFQTLTMKLENLTNPWSPSHSLVQPTLEQTQYSQEHQAAFRFGQTLPKYLLFSSPQKNCWGHRRSYRLQIHSMAEQVLPPGWQEERAVTWARYPLAVTKYRESERYSSSLYNQNDPWDPPVVFEEFLRNNENIEDEDLVAWVTVGFLHIPHSEDVPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPQDKGLNRVQRWIPEDRRCLVSPPFSYNGTYKPV
  
Inhibitor
Name:
BDBM50046192
Synonyms:
6-((E)-{[(E)-amino(hydrazono)methyl]hydrazono}methyl)pyridine-2-carboximidamide | CHEMBL149976
Type:
Small organic molecule
Emp. Form.:
C8H12N8
Mol. Mass.:
220.2345
SMILES:
NC(=N)c1cccc(CNN=C(N)N=N)n1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: