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Target
Amiloride-sensitive amine oxidase [copper-containing]
Ligand
BDBM50046207
Substrate
n/a
Meas. Tech.
ChEBML_53893
IC50
760±n/a nM
Citation
 Stanek, J; Caravatti, G; Capraro, HG; Furet, P; Mett, H; Schneider, P; Regenass, U S-adenosylmethionine decarboxylase inhibitors: new aryl and heteroaryl analogues of methylglyoxal bis(guanylhydrazone). J Med Chem 36:46-54 (1993) [PubMed]  Article 
Target
Name:
Amiloride-sensitive amine oxidase [copper-containing]
Synonyms:
ABP | AOC1_RAT | Abp1 | Amiloride-binding protein | Aoc1 | DAO | Diamine oxidase | Histaminase
Type:
PROTEIN
Mol. Mass.:
85028.72
Organism:
Rattus norvegicus
Description:
ChEMBL_53893
Residue:
746
Sequence:
MCLAFGWAAVILVLQTVDTASAVRTPYDKARVFADLSPQEIKAVHSFLMNREELGLQPSKEPTLAKNSVFLIEMLLPKKKHVLKFLDEGRKGPNREARAVIFFGAQDYPNVTEFAVGPLPRPYYIRALSPRPGHHLSWSSRPISTAEYDLLYHTLKRATMPLHQFFLDTTGFSFLGCDDRCLTFTDVAPRGVASGQRRSWFIVQRYVEGYFLHPTGLEILLDHGSTDVQDWRVEQLWYNGKFYNNPEELARKYAVGEVDTVVLEDPLPNGTEKPPLFSSYKPRGEFHTPVNVAGPHVVQPSGPRYKLEGNTVLYGGWSFSYRLRSSSGLQIFNVLFGGERVAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGSVTHELAPGIDCPETATFLDAFHYYDSDGPVHYPHALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGYVLVLRTTSTVYNYDYIWDFIFYSNGVMEAKMHATGYVHATFYTPEGLRHGTRLQTHLLGNIHTHLVHYRVDMDVAGTKNSFQTLTMKLENLTNPWSPSHSLVQPTLEQTQYSQEHQAAFRFGQTLPKYLLFSSPQKNCWGHRRSYRLQIHSMAEQVLPPGWQEERAVTWARYPLAVTKYRESERYSSSLYNQNDPWDPPVVFEEFLRNNENIEDEDLVAWVTVGFLHIPHSEDVPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPQDKGLNRVQRWIPEDRRCLVSPPFSYNGTYKPV
  
Inhibitor
Name:
BDBM50046207
Synonyms:
6-((E)-{[(E)-[(2E)-2-({6-[(E)-amino(imino)methyl]pyridin-2-yl}methylene)hydrazino](imino)methyl]hydrazono}methyl)pyridine-2-carboximidamide | CHEMBL151001
Type:
Small organic molecule
Emp. Form.:
C15H17N11
Mol. Mass.:
351.3692
SMILES:
NC(=N)c1cccc(C=NNC(=N)NN=Cc2cccc(n2)C(N)=N)n1 |w:15.15,8.7|
Structure:
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