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Target
85/88 kDa calcium-independent phospholipase A2
Ligand
BDBM50046268
Substrate
n/a
Meas. Tech.
ChEMBL_156048 (CHEMBL760624)
IC50
>100±n/a nM
Citation
 Zupan, LA; Weiss, RH; Hazen, SL; Parnas, BL; Aston, KW; Lennon, PJ; Getman, DP; Gross, RW Structural determinants of haloenol lactone-mediated suicide inhibition of canine myocardial calcium-independent phospholipase A2. J Med Chem 36:95-100 (1993) [PubMed]  Article 
Target
Name:
85/88 kDa calcium-independent phospholipase A2
Synonyms:
Calcium-independent phospholipase A2 | PLA2G6 | PLPL9_HUMAN | PLPLA9
Type:
PROTEIN
Mol. Mass.:
89913.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_156048
Residue:
806
Sequence:
MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLVNPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSWSVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHGVPAEQGSAAPHHPFSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMRDEKRTHDHLLCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGMYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFRNYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVNALWETEVYIYEHREEFQKLIQLLLSP
  
Inhibitor
Name:
BDBM50046268
Synonyms:
6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyran-2-one | 6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tetrahydro-pyran-2-one | BTNP | CHEMBL6206
Type:
Small organic molecule
Emp. Form.:
C16H13BrO2
Mol. Mass.:
317.177
SMILES:
Br\C=C1/CCC(C(=O)O1)c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: