Reaction Details Report a problem with these data
Target
Retinoic acid receptor beta
Ligand
BDBM50052959
Substrate
n/a
Meas. Tech.
ChEMBL_195642 (CHEMBL795960)
Kd
10000±n/a nM
Citation
 Beard, RL; Colon, DF; Song, TK; Davies, PJ; Kochhar, DM; Chandraratna, RA Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid. J Med Chem 39:3556-63 (1996) [PubMed]  Article 
Target
Name:
Retinoic acid receptor beta
Synonyms:
Nr1b2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RARB_MOUSE | Rarb
Type:
PROTEIN
Mol. Mass.:
53344.93
Organism:
Mus musculus
Description:
ChEMBL_195641
Residue:
482
Sequence:
MSTSSHACPVPAVRGHMTHYPAAPYPLLFPPVIRGLSLPPLHGLHGHPPPSGCSTPSPASVGQACQRTTGGSQFAASTKWTPSLNAAIETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEPSKQECTESYEMTAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPSSSGNIAEHSPSVSPSSVENSGVSQSPLLQ
  
Inhibitor
Name:
BDBM50052959
Synonyms:
4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalene-2-sulfinyl)-benzoic acid | CHEMBL324960
Type:
Small organic molecule
Emp. Form.:
C22H26O3S
Mol. Mass.:
370.505
SMILES:
Cc1cc2c(cc1S(=O)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
Structure:
Search PDB for entries with ligand similarity: